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    瀏覽量:
    1038

    Maleimide PEG Hydroxyl

    零售價
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    瀏覽量:
    1038
    產品編號
    A5036
    數量
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    產品代號
    MAL-PEG-OH
    產品純度
    ≥ 95%
    包裝規格
    1g, 10g, 100g等(特殊包裝需收取分裝費用)
    分子量
    2000 Da,3500 Da, 5000 Da, 7500 Da等
    如需其他分子量,請聯系 sales@jenkem.com 或 010-62983737

    科研客戶小批量一鍵采購地址(小于50克):

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    參考文獻

      鍵凱科技提供高品質馬來酰亞胺基聚乙二醇羥基產品,產品取代率≥95%。

      鍵凱科技生產的異雙功能馬來酰亞胺PEG羥基產品通常用作兩種不同化學物質的交聯劑或間隔物。此異功能PEG衍生物中的PEG部分可提供水溶性、生物相容性及柔性。此產品專門應用于抗體偶聯藥物(ADC’s)的開發。

      鍵凱科技提供MAL-PEG-OH分子量2000 Da,3500 Da, 5000 Da, 7500 Da的產品1克和10克包裝。

      鍵凱科技提供分裝服務,需要收取分裝費用,如果您需要分裝為其他規格請與我們聯系。

      鍵凱科技同時提供其他分子量的MAL-PEG-OH衍生物產品,如你需要請與我司sales@jenkem.com聯系。

      鍵凱科技提供大批量生產產品及GMP級別產品,如需報價請與我們聯系。

     

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      References:

      1. Xu, X., et al., Efficient and targeted drug/siRNA co-delivery mediated by reversibly crosslinked polymersomes toward anti-inflammatory treatment of ulcerative colitis (UC), Nano Research, 2019, 1-9.

      2. Mozhi, A., et al., Nrp-1 receptor targeting peptide-functionalized TPGS micellar nanosystems to deliver 10-hydroxycampothecin for enhanced cancer chemotherapy, International Journal of Pharmaceutics, 2018, 547(1–2), P. 582-592.

      3. Sarmanova, O.E., et al., A method for optical imaging and monitoring of the excretion of fluorescent nanocomposites from the body using artificial neural networks, Nanomedicine: Nanotechnology, Biology and Medicine, 2018, 14(4), pp.1371-1380.

      4. Fang, Z., et al., Targeted osteosarcoma chemotherapy using RGD peptide-installed doxorubicin-loaded biodegradable polymeric micelle, Biomedicine & Pharmacotherapy, 2017, V. 85, P. 160-168.

      5. Wang, Y., et al., Quantum-Dot-Based Theranostic Micelles Conjugated with an Anti-EGFR Nanobody for Triple-Negative Breast Cancer Therapy, ACS applied materials & interfaces, 2017, 9(36):30297-305.

      6. Mondal, G., et al., EGFR-Targeted Polymeric Mixed Micelles Carrying Gemcitabine for Treating Pancreatic Cancer, Biomacromolecules, 2016, 17 (1), pp 301–313.

      7. Li, C., et al., Design, preparation and characterization of cyclic RGDfK peptide modified poly (ethylene glycol)-block-poly (lactic acid) micelle for targeted delivery, Materials Science and Engineering: C, 2016.

      8. Gu, D., et al., Amphiphilic core cross-linked star polymers as water-soluble, biocompatible and biodegradable unimolecular carriers for hydrophobic drugs, Polym. Chem., 2015, 6, 6475-6487.

      9. Prabhakar, N., et al., Functionalization of graphene oxide nanostructures improves photoluminescence and facilitates their use as optical probes in preclinical imaging, Nanoscale, 2015, 7, 10410-10420.

      10. Ding, G.-B., et al., Integrin αVβ3-Targeted Magnetic Nanohybrids with Enhanced Antitumor Efficacy, Cell Cycle Arrest Ability, and Encouraging Anti-Cell-Migration Activity, ACS Appl. Mater. Interfaces, 2014, 6 (19), p: 16643–16652.

      11. Song, W., et al., Anti-tumor efficacy of c(RGDfK)-decorated polypeptide-based micelles co-loaded with docetaxel and cisplatin. Biomaterials, 2014, 35(9): p. 3005-3014.

      12. Liu, J., et al., Effect of site-specific PEGylation on the fibrinolytic activity, immunogenicity, and pharmacokinetics of staphylokinase, Acta Biochim Biophys Sin, 2014, 46 (9): 782-791.

      13. Li, Y., et al., Docetaxel-Encapsulating Small-Sized Polymeric Micelles with Higher Permeability and Its Efficacy on the Orthotopic Transplantation Model of Pancreatic Ductal Adenocarcinoma, Int. J. Mol. Sci., 2014, 15(12), 23571-23588.

      14. Pridgen, E. M., et al., Transepithelial Transport of Fc -Targeted Nanoparticles by the Neonatal Fc Receptor for Oral Delivery, Sci Transl Med., 2013, 5(213).

      15. Shen, J., et al., Poly(ethylene glycol)-block-poly(d,l-lactide acid) micelles anchored with angiopep-2 for brain-targeting delivery, Journal of Drug Targeting, 2011, 19:3.

      16. Zhan, C., et al., Loop 2 of Ophiophagus hannah Toxin b Binds with Neuronal Nicotinic Acetylcholine Receptors and Enhances Intracranial Drug Delivery, Mol. Pharmaceutics, 2010, 7(6), p: 1940–1947.

      17. Zhan, C., et al., Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel anti-glioblastoma effect, Journal of Controlled Release, 2010, 143:1, P. 136-142.

           18.Dogan, A. Leveraging thermodynamic interactions to enhance drug delivery. Diss. Case Western Reserve University, 2021.

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